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1

Effects of formulation and route of administration on the systemic availability of Ex-RAD®, a new radioprotectant, in preclinical species

Amy W. Chun, Robert E. Freshwater, David R. Taft, Amanda M. Gillum, Manoj Maniar

Journal:

Biopharmaceutics & Drug Disposition

Year:

2011

Language:

english

File:

PDF, 253 KB

english, 2011

2

Use of liquid chromatography and mass spectroscopy to select an oligomer representative of polyester hydrolysis pathways

Manoj L Maniar, Devendra S. Kalonia, Anthony P. Simonelli

Journal:

Journal of Pharmaceutical Sciences

Year:

1989

Language:

english

File:

PDF, 535 KB

english, 1989

3

Determination of specific rate constants of specific oligomers during polyester hydrolysis

Manoj L. Maniar, Devendra S. Kalonia, Anthony P. Simonelli

Journal:

Journal of Pharmaceutical Sciences

Year:

1991

Language:

english

File:

PDF, 557 KB

english, 1991

4

Alkaline hydrolysis of oligomers of tartrate esters: Effect of a neighboring carboxyl on the reactivity of ester groups

Manoj L. Maniar, Devendra S. Kalonia, Anthony P. Simonelli

Journal:

Journal of Pharmaceutical Sciences

Year:

1992

Language:

english

File:

PDF, 557 KB

english, 1992

5

Polyanhydrides: V. Branched polyanhydrides

Manoj Maniar, Xiadong Xie, Abraham J. Domb

Journal:

Year:

1990

Language:

english

File:

PDF, 529 KB

english, 1990

6

Development and validation of a sensitive liquid chromatographic method for the analysis of a novel radioprotectant: ON 01210.Na

Parina P. Fernandes, Manoj Maniar, Alekha K. Dash

Journal:

Journal of Pharmaceutical and Biomedical Analysis

Year:

2007

Language:

english

File:

PDF, 769 KB

english, 2007

7

Administration of ON 01210.Na after exposure to ionizing radiation protects bone marrow cells by attenuating DNA damage response

Shubhankar Suman, Manoj Maniar, Albert J Fornace, Kamal Datta

Journal:

Radiation Oncology

Year:

2012

Language:

english

File:

PDF, 640 KB

english, 2012

8

Controlled release of 4-hydroperoxycyclophosphamide from the fatty acid dimer-sebacic acid copolymer

Kwame G. Buahin, Kevin D. Judy, Carol Hartke, Abraham J. Domb, Manoj Maniar, O. Michael Colvin, Henry Brem

Journal:

Polymers for Advanced Technologies

Year:

1992

Language:

english

File:

PDF, 542 KB

english, 1992

9

Degradable polymers for site-specific drug delivery

Abraham Domb, Shimon Amselem, Jaymin Shah, Manoj Maniar

Journal:

Polymers for Advanced Technologies

Year:

1992

Language:

english

File:

PDF, 1.44 MB

english, 1992

10

A novel method to determine the molecular weight of the oligomers of biodegradable polymer

Manoj L. Maniar, Siddharth J. Advant, Devendra S. Kalonia, Anthony P. Simonelli

Journal:

Polymers for Advanced Technologies

Year:

1992

Language:

english

File:

PDF, 708 KB

english, 1992

11

Absorbable biopolymers derived from dimer fatty acids

Abraham J. Domb, Manoj Maniar

Journal:

Journal of Polymer Science Part A: Polymer Chemistry

Year:

1993

Language:

english

File:

PDF, 789 KB

english, 1993

12

Preclinical pharmacokinetics and in

Amy W. Chun, Stephen C. Cosenza, David R. Taft, Manoj Maniar

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2009

Language:

english

File:

PDF, 293 KB

english, 2009

13

pH-Dependent solubility and dissolution of bupivacaine and its relevance to the formulation of a controlled release system

Jaymin C. Shah, Manoj Maniar

Journal:

Journal of Controlled Release

Year:

1993

Language:

english

File:

PDF, 1.03 MB

english, 1993

14

Controlled release of a local anesthetic from fatty acid dimer based polyanhydride

Manoj Maniar, Abraham Domb, Andrew Haffer, Jaymin Shah

Journal:

Journal of Controlled Release

Year:

1994

Language:

english

File:

PDF, 651 KB

english, 1994

15

Water uptake in to polyanhydride devices: kinetics of uptake and effects of model compounds incorporated, and device geometry on water uptake

Eun-Seok Park, Manoj Maniar, Jaymin Shah

Journal:

Journal of Controlled Release

Year:

1996

Language:

english

File:

PDF, 865 KB

english, 1996

16

Effects of model compounds with varying physicochemical properties on erosion of polyanhydride devices

Eun-Seok Park, Manoj Maniar, Jaymin Shah

Journal:

Journal of Controlled Release

Year:

1996

Language:

english

File:

PDF, 850 KB

english, 1996

17

Directed therapy for patients with myelodysplastic syndromes (MDS) by suppression of cyclin D1 with ON 01910.Na

Matthew J. Olnes, Aarthie Shenoy, Barbara Weinstein, Loretta Pfannes, Kelsey Loeliger, Zachary Tucker, Xin Tian, Minjung Kwak, Francois Wilhelm, Agnes S.M. Yong, Irina Maric, Manoj Maniar, Phillip Sch

Journal:

Leukemia Research

Year:

2012

Language:

english

File:

PDF, 658 KB

english, 2012

18

Influence of physicochemical properties of model compounds on their release from biodegradable polyanhydride devices

Eun-Seok Park, Manoj Maniar, Jaymin C Shah

Journal:

Journal of Controlled Release

Year:

1997

Language:

english

File:

PDF, 960 KB

english, 1997

19

Biodegradable polyanhydride devices of cefazolin sodium, bupivacaine, and taxol for local drug delivery: preparation, and kinetics and mechanism of in vitro release

Eun-Seok Park, Manoj Maniar, Jaymin C Shah

Journal:

Journal of Controlled Release

Year:

1998

Language:

english

File:

PDF, 205 KB

english, 1998

20

Disposition of ON 01210.Na (Ex-RAD (R) ), a novel radioprotectant, in the isolated perfused rat liver: Probing metabolic inhibition to increase systemic exposure

Tamhane, Mitalee, Maniar, Manoj, Ren, Chen, Benzeroual, Kenza E., Taft, David R.

Journal:

Journal of Pharmaceutical Sciences

Year:

2013

Language:

english

File:

PDF, 322 KB

english, 2013

21

Radiation Protection by a New Chemical Entity, Ex-Rad™: Efficacy and Mechanisms

Ghosh, Sanchita P., Perkins, Michael W., Hieber, Kevin, Kulkarni, Shilpa, Kao, Tzu-Cheg, Reddy, E. Premkumar, Reddy, M. V Ramana, Maniar, Manoj, Seed, Thomas, Kumar, K. Sree

Journal:

Radiation Research

Year:

2009

Language:

english

File:

PDF, 518 KB

english, 2009

22

Clinical activity and safety of the dual pathway inhibitor rigosertib for higher risk myelodysplastic syndromes following DNA methyltransferase inhibitor therapy

Silverman, Lewis R., Greenberg, Peter, Raza, Azra, Olnes, Matthew J., Holland, James F., Reddy, Premkumar, Maniar, Manoj, Wilhelm, Francois

Journal:

Hematological Oncology

Year:

2015

Language:

english

File:

PDF, 1.03 MB

english, 2015

23

Determination of intestinal permeability of rigosertib (ON 01910.Na, Estybon): correlation with systemic exposure

White, Michael P., Babayeva, Mariana, Taft, David R., Maniar, Manoj

Journal:

Journal of Pharmacy and Pharmacology

Year:

2013

Language:

english

File:

PDF, 440 KB

english, 2013

24

Phase I clinical trial of oral rigosertib in patients with myelodysplastic syndromes

Komrokji, Rami S., Raza, Azra, Lancet, Jeffrey E., Ren, Chen, Taft, David, Maniar, Manoj, Wilhelm, Francois, List, Alan F.

Journal:

British Journal of Haematology

Year:

2013

Language:

english

File:

PDF, 146 KB

english, 2013

25

Radiation Protection by a New Chemical Entity, Ex-Rad™: Efficacy and Mechanisms

Sanchita P. Ghosh, Michael W. Perkins, Kevin Hieber, Shilpa Kulkarni, Tzu-Cheg Kao, E. Premkumar Reddy, M. V. Ramana Reddy, Manoj Maniar, Thomas Seed and K. Sree Kumar

Journal:

Radiation Research

Year:

2009

Language:

english

File:

PDF, 1.81 MB

english, 2009

26

Determination of Degradation Kinetics and Effect of Anion Exchange Resin on Dissolution of Novel Anticancer Drug Rigosertib in Acidic Conditions

Patel, Hardikkumar H., Maniar, Manoj, Ren, Chen, Dave, Rutesh H.

Journal:

AAPS PharmSciTech

Year:

2017

Language:

english

File:

PDF, 1.03 MB

english, 2017

27

Effect of Gender on the Pharmacokinetics of ON 123300, A Dual Inhibitor of ARK5 and CDK4/6 for the Treatment of Cancer, in Rats

Mudunuru, Jennypher, Ren, Chen, Taft, David R., Maniar, Manoj

Journal:

European Journal of Drug Metabolism and Pharmacokinetics

Year:

2019

File:

PDF, 807 KB

2019

28

OUTCOMES ASSOCIATED WITH PERCUTANEOUS CORONARY INTERVENTION PRIOR TO TRANSCATHETER AORTIC VALVE IMPLANTATION

Thangam, Manoj, Thakker, Prashanth, Husaini, Mustafa, Posenau, John, Sintek, Marc, Kachroo, Puja, Lasala, John, Melby, Spencer, Quader, Nishath, Maniar, Hersh, Singh, Jasvindar, Kurz, Howard, Bach, Ri

Journal:

Journal of the American College of Cardiology

Year:

2019

File:

PDF, 272 KB

2019

29

Rigosertib in combination with azacitidine in patients with myelodysplastic syndromes or acute myeloid leukemia: Results of a phase 1 study

Navada, Shyamala C., Garcia-Manero, Guillermo, OdchimarReissig, Rosalie, Pemmaraju, Naveen, Alvarado, Yesid, Ohanian, Maro N., John, Rosmy B., Demakos, Erin P., Zbyszewski, Patrick S., Maniar, Manoj,

Journal:

Leukemia Research

Year:

2020

File:

PDF, 248 KB

2020

30

Transcatheter Aortic Valve Replacement (TAVR) in Patients with Paradoxical Low-Flow Low-Gradient Aortic Stenosis

Thakker, Prashanth, Husaini, Mustafa, Thangam, Manoj, Lindman, Brian, Maniar, Hersh, Quader, Nishath, Melby, Spencer, Sintek, Marc, Kachroo, Puja, Lasala, John, Zajarias, Alan

Journal:

Structural Heart

Year:

2020

File:

PDF, 1.40 MB

2020

31

[Society of Petroleum Engineers SPE Annual Technical Conference and Exhibition - Calgary, Alberta, Canada (2019-09-23)] SPE Annual Technical Conference and Exhibition - Improving Sweep Efficiency by Zonal Isolation Using High Expansion Ratio Inflatable Plugs - A Case Study II

Kumar, Manish, Varma, Nakul, Dangwal, Gaurav, Gupta, Manoj, Srivastava, Preyas, Shrivastava, Pranay, Maniar, Chintan, Nekkanti, Satish, Bohra, Avinash, Chandak, Krishana, Pandey, Arpita, Nagar, Ankesh

File:

PDF, 1.96 MB